Griff Hamlin Lessons: Blues Rhythm Guitar Lesson The I IV I7 Move
For blues comping (playing blues rhythm guitar) this is a move that gets used on all kinds of tunes...
Slow blues, shuffle blues, straight feel songs... really doesn't matter, this will work.
It's also one of those "set and forget" moves - honestly don't worry too much about why it works (I'll tell you) but concentrate on experimenting with it and really making it your own.
Play it - a lot - and get it down so it works for you. I promise you'll be glad you did.